Sunday, December 29, 2019
What Drives Adult Personality Development - 1542 Words
Question #1 According to Specht, Bleidorn, Dennisen, Henneck, Huteman, Kandler, Luhmann, Orth, Reitz and Zimmermanââ¬â¢s article (2014) What Drives Adult Personality Development? A Comparison of Theoretical Perspectives and Empirical Evidence In terms of adult personality development, the most prominent perspectives utilize genetic and environmental factors into their models. Some examples of these theories consist of the five factor theory of personality and neo-social analytic theory (Specht et al., 2014). McCray and Costaââ¬â¢s five factor theory focuses on biological maturation and not life experiences (Specht et al., 2014). Meaning that innate biological processes may parallel physical fluctuations experienced in puberty. Many organisms go through stages of crucial development and reproduction events that include sexual and physical maturation (Specht et al., 2014). In turn, McCray and Costa hypothesized that higher levels of Openness to experience and Extraversion are detrimental to finding a mating partner while Conscientiousness and Agreeableness facilitate raising a family (Specht et al., 2014). One of the limitations associated with this theory is that individual differences appear around the age of 30 based on the empirical evidence (Specht et al., 2014). Thus, the empirical data suggest that more changes occur and this theory doesnââ¬â¢t encompass all those changes. This perspective also fails to acknowledge normal ranging common life experiences (Specht et al., 2014).S how MoreRelatedEssay on Freud V Erickson1371 Words à |à 6 Pagestheories of development relied heavily on the belief that infantile sexuality must be seen as an integral part of a broader developmental theory of human personality. This had its origins in, and was a generalization of, Breuers earlier discovery that traumatic childhood events could have devastating negative effects upon the adult individual, and took the form of the general thesis that early childhood sexual experiences were the crucial factors in the determination of the adult personality.(Freud2)Read MoreFreud s Psychoanalytic Theory Of Personality1384 Words à |à 6 Pages In this paper I am going to talk about Sigmund Freudââ¬â¢s psychoanalytic theory of personality. I will describe what his theory is about and about what my thoughts are about if I would use this technique or not in my way in counseling. I will also describe different ways that I would still use the Freudââ¬â¢s technique but in my own u nique way. Sigmund Freud s psychoanalytic theory of personality argues that human behavior is the result of the interactions among three component parts of the mind: theRead MoreWhat Can Psychology Teach Us About Human Development?1558 Words à |à 7 PagesPSYCHOLOGY ESSAY WHAT CAN PSYCHOLOGY TEACH US ABOUT HUMAN DEVELOPMENT? WORDCOUNT 1532 INTRODUCTION Psychology evolved out of both philosophy and biology. Discussions on the two subjects date as far back as the early Greek thinkers such as Aristotle and Socrates. The word psychology is derived from the Greek word ââ¬Ëpsycheââ¬â¢ meaning ââ¬Ësoulââ¬â¢ or ââ¬Ëmindââ¬â¢. Psychology is both an applied and academic field, that is the scientific study Of behaviour and experience. Research into psychology helps us toRead MorePsychological Aspects Of Criminal Behavior1565 Words à |à 7 Pagespatterns and trends unique to each criminal offenderââ¬â¢s past. Intelligence, learning, and personality all play into the likelihood for someone to exhibit any kind of criminal behavior. In order to understand the root causes of criminal behavior and deviance of an offender, one must identify the particular parts of the human personality that play into the psychodynamics and psychosexual stages of development during childhood. From there mental disorders and other antisocial behavior may become apparentRead MoreA Study On Twins, Twins Separated At Birth Through Adoption1275 Words à |à 6 Pagesenvironment in which they grew up in and their genes. Schulsinger (1972) carried out the first adoption study in Denmark. His theory was to compare adopted adults, some adults had been diagnosed as psychopaths and others hadnââ¬â¢t. There was a lot of criticism regarding his theory because Schulsinger used his own criteria to diagnose particular adults with psychopathic behaviour. Another criminologist who developed a theory around adoption was Crowe, he studied those that came from families with criminalRead MoreEssay about Explanations of Personality Development701 Words à |à 3 PagesExplanations of Personality Development According to Sigmund Freud, what we do and why we do it, who we are and how we became this way are all related to our sexual drive. Differences in personalities originate in differences in childhood sexual experiences. In the Freudian psychoanalytical model, child personality development is discussed in terms of psychosexual stages. In his Three Essays on Sexuality (1915), Freud outlined five stages of manifestations of theRead MorePsy/405 Klein vs. Erikson Debate Essay960 Words à |à 4 PagesEriksonââ¬â¢s Post-Freudian Theory in regards to their describing of individual personality characteristics along with interpersonal relations. Team Klein will begin the debate: Jessica - On the positive aspects of Kleinââ¬â¢s object theory on individual personality characteristics is how an infantââ¬â¢s experience can shape their future personality. One is the object of the breast, which later perceives total control and this drives satisfaction called the id. According to Burch (1988), ââ¬Å"Good experiencesRead MoreFreuds Work with Humans Relation to the Mind791 Words à |à 3 PagesLittle was known about the development of humans in relation to the mind and what affected its development until, Sigmund Freud, made it his life work. Freud was born in Frieberg, Moravia (which is now part of the Czech Republic) in 1856. His family eventually moved to Vienna where he began his life work and remained until the last years of his life (other than WWII, as being Jewish he was allowed to leave for England, but returned after the conclusion). He always considered himself a scientist firstRead MorePsychodynamic Theory1497 Words à |à 6 Pagestheories and t hose of his followers. Freudââ¬â¢s psychoanalysis is both a theory and a therapy. His theory had the main focus that: * Children pass thru a series of age-dependent stages during development * Each stage has a designated ââ¬Å"pleasure zoneâ⬠and ââ¬Å"primary activityâ⬠,human motivation is guided by the drive to seek pleasure * Each stage requires resolution of a particular conflict/task * Failure to successfully navigate a stageââ¬â¢s particular conflict/ task is known as Fixation * LeavingRead MoreThe Importance Of Extracurricular Activities1265 Words à |à 6 PagesMany people in school, no matter what age or grade one may be in, are involved in some type of extracurricular. Many people also donââ¬â¢t get to choose what extracurricular they begin to partake in due to their parents or guardians deciding what they would like their child to participate in, more often than not at a very young age. Whether it be attached to the school they attend or not, many people arenââ¬â¢t aware of the many positive effects that it may have on their own self, or their child. While
Saturday, December 21, 2019
Capturing Real Life in Jane Austens Emma Essay - 2772 Words
Capturing Real Life in Emma Jane Austen deliberately confined herself to the realistic portrayal of a segment of contemporary English life-upper middle-class society. The heroine, Emma Woodhouse, lives on her fathers estate at Hartfield which is in effect an adjunct of the village of Highbury in spite of its separate lawns and shrubberies. Mr. Westons estate of Randals is in the parish of Highbury, and Mr. Knightleys Donwell Abbey is situated in the neighbouring parish, within comfortable walking distance. Here life is concentrated within itself and separated from London which although only sixteen miles away was much beyond...daily reach. Significantly, Emma has never visited London, never been to the seaside, never visitedâ⬠¦show more contentâ⬠¦Coles carriage horses returning from exercise, or a stray letter-boy on an obstinate mule, were the liveliest objects she could presume to expect; and when her eyes fell only on the butcher with his tray, a tiny old woman travelling homewards from the shop with her full basket, two curs quarrelling over a dirty bone, and a string of dawdling children round the bakers little bow-window eyeing the gingerbread, she knew she had no reason to complain, and was amused enough; quite enough still to stand at the door. In such a narrow society gossip helps to relieve the tedium. This gossip may be harmless - Mr. Frank Churchills coming to visit his father and stepmother; speculation about Mr. Eltons fiancee, Miss Augusta Hawkins of Bristol; excited accounts (becoming more and more exaggerated with each telling) of Harriets gallant rescue from the gypsies by Frank Churchill. However, gossip can also be malicious, as we shall see when Emma confides in Frank Churchill her unfounded suspicion that Jane Fairfaxs pianoforte is a gift from a secret admirer, Mr. Dixon, husband of Janes dearest friend Miss Campbell. Highbury society can also be unbearably claustrophobic. This is symbolically highlighted when Emma is trapped alone with Mr. Elton in her carriage on the journey home from the Christmas Eve dinner-party at Randals. After she has rejected the vicars proposal of marriage out of hand, they have no choice but to continue theShow MoreRelatedComparing Clueless and Emma Essay1816 Words à |à 8 PagesCLUELESS VS. EMMA Adaptations of Jane Austenââ¬â¢s, Emma, are usually period pieces diligent in capturing and replicating the manners, dress, language and values of the original text. Clueless, written and directed by Amy Heckerling, deviates drastically from the norm, as the film is not a period piece. While Emma is set in the early nineteenth century in the country village of Highbury, sixteen miles out of London, England, Clueless is set in Bronson Alcott High School almost two hundred years laterRead MoreGoal Movie Review10720 Words à |à 43 Pagesmust prove that heââ¬â¢s got the grit and the game to win a contract with one of the most prestigious football clubs in the world. Muddy fields, cold winds and crunching blows from teammatesââ¬ânot to mention personal woes, injuries, and the temptations of life in the fast laneââ¬âare just a few of the obstacles Santiago must overcome to triumph in the heady, heart-pounding world of international football. 1 Directed by Danny Cannon, ââ¬Å"Goal! The Dream Beginsâ⬠stars up and coming Latino actor Kuno Becker. SomeRead MoreLogical Reasoning189930 Words à |à 760 Pagesproblem without bringing in the most relevant information. This first chapter explains what it means to be logicalââ¬âto reason logically. It demonstrates the usefulness of logical reasoning as a means to making more effective decisions about your own lifeââ¬âdecisions about what to believe and decisions about what to do. The chapter begins a systematic program of study of all the major topics regarding logical reasoning. Along the way, the book focuses on developing the following five skills: (1) writing
Friday, December 13, 2019
Medical Immunology Free Essays
MEDICAL IMMUNOLOGY SEROLOGY Terence L. Eday, RMT, MT(ASCPi), MPH College of Medical Technology / Medical Laboratory Science University of Perpetual Help System DALTA Historical Perspective â⬠¢ 1773, Voltaire reported on an ancient Chinese custom where dried and powdered small pox scabs were inhaled â⬠¢ 1798, Edward Anthony Jenner, Smallpox vaccination â⬠¢ 1862, Ernst Haekel, Recognition of phagocytosis 1877, Paul Erlich, recognition of mast cells Historical Perspective â⬠¢ 1879, Louis Pasteur, Attennuated chicken cholera vaccine development â⬠¢ 1883, Ellie Metchnikoff developed the cellular theory of immunity through phagocytosis; phagocytic theory; cellular theory of vaccination â⬠¢ 1885, Pasteur discovered therapeutic vaccination; first report of live ââ¬Å"attenuatedâ⬠vaccine for rabies Historical Perspective 1888, Pierre Roux Alexander Yersin, Bacterial toxins (Yersinia pestis) â⬠¢ 1888, George Nuttall, Bactericidal action of blood â⬠¢ 189 0, Emil von Behring and Kitasata introduced passive immunization into modern medicine; humoral theory of immunity â⬠¢ 1891, Robert Koch demonstrated the cutaneous (delayed-type) hypersensitivity â⬠¢ 1894, Richard Pfeiffer, Bacteriolysis Historical Perspective (1 of 6 ) 1895, Jules Bordet, Complement and antibody activity in bacteriolysis â⬠¢ 1900, Paul Ehrlich, responsible for the antibody formation theory â⬠¢ 1901, Karl Landsteiner, A, B, and O â⬠¢ 1901-8, Carl Jensen Leo Loeb, Transplantable tumors â⬠¢ 1902, Paul Portier Charles Richet, Anaphylaxis Historical Perspective (1 of 6 ) â⬠¢ 1903, Nicolas Maurice Arthus, discovered the Arthus reaction of intermediate hypersensitivity â⬠¢ 1903, Almroth Wright and Stewart Douglas observed the humoral component, opsonin â⬠¢ 1906, Clemens von Pirquet, coined the word allergy â⬠¢ 1907, Svante Arrhenius, coined the term immunochemistry Historical Perspective â⬠¢ 1910, Emil von Dungern, Ludwik Hirszfeld, Inheritance of ABO blood groups â⬠¢ 1910, Peyton Rous, Viral immunology theory â⬠¢ 1914, Clarence Little, Genetics theory of tumor transplantation â⬠¢ 1915-20, Leonll Strong Clarence Little, Inbred mouse strains Historical Perspective â⬠¢ 1917, Karl Landsteiner, Haptens â⬠¢ 1921, Carl Prausnitz Heinz Kustner, Cutaneous reactions â⬠¢ 1924, L. Aschoff, Reticuloendothelial system â⬠¢ 1926, Loyd Felton GH Bailey, Isolation of pure antibody preparation â⬠¢ 1938, John Marrack, Antigen-antibody binding hypothesis Historical Perspective 1936, Peter Gorer, Identification of the H2 antigen in mice â⬠¢ 1940, Karl Landsteiner Alexander Weiner, Identification of the Rh Antigens â⬠¢ 1941, Albert Coons, Immunofluorescence technique â⬠¢ 1942, Jules Freund Katherine McDermott, Adjuvants â⬠¢ 1942, Karl Landsteiner Merill Chase, Cellular transfer of sensitivity in guinea pigs (anaphylaxis) Historical Perspective â⬠¢ 1944, Peter Medwar, Immunological hypothesis of allograft rejection â⬠¢ 1948, Astrid Fagraeus, Demonstration of antibody production in plasma B cells â⬠¢ 1948, George Snell, Congenic mouse lines â⬠¢ 1949, Macfarlane Burnet Frank Fenner, Immunological tolerance hypothesis Historical Perspective â⬠¢ 1950, Richard Gershon and K Kondo, Discovery of supressor T cells â⬠¢ 1952, Ogden and Bruton, discovery of agammaglobulinemia (antibody immunodeficiency) â⬠¢ 1953, Morton Simonsen and WJ Dempster, Graft-versus-host reaction â⬠¢ 1953, James Riley Geoffrey West, Discovery of histamine in mast cells Historical Perspective â⬠¢ 1953, Rupert Billingham, Leslie Brent, Peter Medwar, Milan Hasek, Immunological tolerance hypothesis â⬠¢ 1955-1959, Niels Jerne, David Talmage, Macfarlane Burnet, Clonal Selection Theory â⬠¢ 1957, Ernest Witebsky et all. We will write a custom essay sample on Medical Immunology or any similar topic only for you Order Now Induction of autoimmunity in animals â⬠¢ 1957, Alik Isaacs Jean Lindemann, Discovery of interferon (cytokine) Historical Perspective â⬠¢ 1958-62, Jean Dausset et al. , Human leukocyte antigens â⬠¢ 1959-62, Rodney Porter et al. , Discovery of antibody structure â⬠¢ 1959, James Gowans, Lympocyte circulation â⬠¢ 1961-62, Jaques Miller et al. , Discovery of thymus involvement in cellular immunity â⬠¢ 1961-62, Noel Warner et al. , Disctinction of cellular and humoral immune response Historical Perspective â⬠¢ 1963, Jacques Oudin et al. Antibody isotypes â⬠¢ 1964-68, Anthony Davis et al. , T and B cell cooperation in immune response â⬠¢ 1965, Thomas Tomasi et al. , Secretory immunoglobulin antibodies â⬠¢ 1967, Kimishige Ishizaka et al. , Identification of IgE as the reaginic antibody Historical Perspective â⬠¢ 1971, Donald Bailey, Recombinant inbred mouse strains â⬠¢ 1972, Gerald M. Edelman Rodney Porter, Identification of antibody molecul e â⬠¢ 1974, Rolf Zinkernagel Peter Doherty, MHC restriction â⬠¢ 1975, Kohler and Milstein, First monoclonal antibodies used in genetic analysis Historical Perspective â⬠¢ 1984, Robert Good, Failed treatment of severe combined immunodeficiency (SCID, David the bubble boy) by bone marrow grafting â⬠¢ 1985, Tonegawa, Hood et al. , Identification of immunoglobulin genes â⬠¢ 1985-1987, Leroy Hood et al. , Identification of genes for the T cell receptor â⬠¢ 1986, Monoclonal hepatitis B vaccine Historical Perspective â⬠¢ 1986, Mosmann, Th1 versus Th2 model of T-helper-cell function â⬠¢ 1990, Yamamoto et al. Molecular differences between the genes for blood groups O and A and between those for A and B â⬠¢ 1990, NIH team, Gene therapy for SCID using cultured T cells â⬠¢ 1993, NIH team, Treatment of SCID using genetically altered umbilical cord cells Historical Perspective â⬠¢ 1996-1998, Identification of toll-like receptors â⬠¢ 2001, FOXP3, the gene directing regulatory-T-cell development â⬠¢ 2005, Frazer, Development of human papilloma-virus vaccine The IMMUNE SYTEM What is Immunology? â⠬ ¢ Study of the molecules, cells, organs, and systems responsible for the recognition and disposal of foreign (nonself) material â⬠¢ â⬠¦ ow body components respond and interact â⬠¢ â⬠¦desirable and undesirable consequences of immune interactions â⬠¢ â⬠¦ways in which the immune system can be advantageously manipulated to protect against or treat disease What is Immunity? â⬠¢ Latin word ââ¬Å"immunitasâ⬠, freedom from â⬠¢ It refers to all mechanisms used by the body as protection against environmental agents that are foreign to the body. â⬠¢ Can be either natural (innate or inborn) or acquired (adaptive) Function of the Immune System â⬠¢ Recognize ââ¬Å"selfâ⬠from ââ¬Å"nonselfâ⬠â⬠¢ Defend the body against nonself Physiologic function is to prevent infection and to eradicate established infections (sterilizing immunity) Key Characteristics of the Immune System â⬠¢ Innate immunity â⬠¢ Primary response â⬠¢ Sec ondary response and immunologic memory â⬠¢ Immune response is highly specific â⬠¢ Immune system is tolerant of self-antigens â⬠¢ Immune responses against self-antigens can result in autoimmune diseases â⬠¢ Immune responses against infectious agents do not always lead to elimination of the pathogen (HIV/AIDS) Major Principles of Immunity (immune response): Elimination of many microbial agents through the nonspecific protective mechanisms of the innate immune system. â⬠¢ Cues from the innate immune system inform the cells of the adaptive immune system as to whether it is appropriate to make a response and what type of response to make. Major Principles of Immunity (immune response): â⬠¢ Cells of the adaptive immune system display exquisitely specific recognition of foreign antigens and mobilize potent mechanisms for elimination of microbes bearing such antigens. The immune system displays memory of its previous responses. â⬠¢ Tolerance of self-antigens. Cel ls of the Immune System â⬠¢ Lymphocytes ââ¬â occupy the central stage; determines the specificity of immunity â⬠¢ Dendritic cells (DCs) Langerhan cells â⬠¢ Monocyte/macrophages â⬠¢ Natural killer (NK) cells â⬠¢ Neutrophils â⬠¢ Mast cells Basophils â⬠¢ Eosinophils â⬠¢ Epithelial and stromal cells ââ¬â provides anatomic environment (secretion of critical factors that regulate migration, growth and homeostasis) Lymphoid Tissues and Organs Primary Lymphoid Organs Sites where pre-B and pre-T lymphocytes mature into naive T and B cells in the absence of foreign antigen; â⬠¢ Fetal Liver, Adult bone marrow, and thymus The INNATE IMMUNE SYTEM INNATE IMMUNE SYSTEM â⬠¢ relies on germ line-encoded receptors to detect a limited set of microbial structures that are uniquely associated with microbial infection â⬠¢ not a function of a single defined physiologic system; rather, it is a product of multiple and diverse defense mechanisms Modules of the Innate Immune System â⬠¢ Surface epithelium The phagocyte system ââ¬â critical for the defense against both intracellular and extracellular bacteria as well as fungal pathogens; aided by opsonins â⬠¢ Acute phase response and complement ââ¬â variety of secreted proteins that function in the circulation and in tissue fluids; secreted by the hepatocytes in response to the inflammatory cytokines IL1 and IL-6 Modules of the Innate Immune System â⬠¢ Natural killer (NK) cells are specialized in the elimination of infected host cells and in aiding defense against viral and other intracellular infections through production of cytokines(IFN-? ; regulated by type I interferons (IFN-? /? ) â⬠¢ Mast cells, eosinophils, and basophils are specialized in defense against multicellular parasites, such as helminthes; regulated by several cytokines, including IL-4, IL-5, IL-9, and IL-13 Strategies of Innate Immune Recognition 1. Recognition of microbial nonself ââ¬â ref erred to as pattern recognition, based on the recognition of molecular structures that are unique to microorganisms and not produced by the host 2. Recognition of missing self ââ¬â based on the recognition of molecules expressed only on normal, uninfected cells of the host Targets of Innate Immune Recognition â⬠¢ PAMPs (pathogen-associated molecular patterns) ââ¬â molecular structures produced by microbial pathogens, but not by the host organism â⬠¢ PRRs (pattern recognition receptors) ââ¬â receptors of the innate immune system and represents targets of the innate immune system Targets of Innate Immune Recognition Examples of PAMPs include: (1) LPS of gram-negative bacteria (2) LTA of gram-positive bacteria (3) Peptidoglycans (4) Lipoproteins of bacteria (cell wall) (5) Lipoarabinomannan of mycobacteria (6) dsRNA produced by virus during the infection cycle (7) ? -glucans and mannans found in fungal cell wall Receptors of the Innate Immune System â⬠¢ Broad categories of PRRs: (1) PRRs that signal the presence of infection; expressed on the cell surface or intracellularly Categories of gene products: a. pr oteins and peptides that have direct antimicrobial effector functions (antimicrobial peptides and lysozyme) b. nflammatory cytokines and chemokines (TNF, IL-1, IL-8) c. gene products that control activation of the adaptive immune response (MHC, CD80/CD86, IL-12) Receptors of the Innate Immune System â⬠¢ Broad categories of PRRs: (2) Phagocytic (or endocytic) PRRs; expressed on the surface of macrophages, neutrophils, and dendritic cells(DCs) (3) Secreted PRRs (mannan-binding lectin and peptidoglycan-recognition proteins Function: a. activate complement b. opsonize microbials cells to facilitate their phagocytosis c. ccessory proteins for PAMP recognition by transmembrane receptors (TLR) Receptors of the Innate Immune System â⬠¢ Toll-like Receptors ââ¬â comprise a family of type 1 transmembrane receptors characterized by leucine rich repeats (LRRs) in the extracellular portion and an intracellular TIR (Toll/IL-1 receptor) domain; grouped into two classes: (1) TLRs 1, 2, 4 , 5, and 6 are expressed on the plasma membrane and detect bacterial and fungal cell wall components; (2) TLRs 3, 7, and 9 are expressed in endosomal compartments and recognize viral nucleic acids Toll-like receptor 4 (TLR4) â⬠¢ expressed predominantly in the cells of the immune system, including macrophages, DC, neutrophils, mast cells, and B cells â⬠¢ also expressed on endothelial cells, fibroblasts, surface epithelial cells, and muscle cell â⬠¢ Signal transducing receptor for LPS, heat sensitive protein associated with the cell walls of MTB â⬠¢ Together with CD14 shown to mediate responsiveness to the fusion (F) protein of RSV Toll-like receptor 2 (TLR2) â⬠¢ Involved in recognition of LTA and peptidoglycan from gram-positive bacteria, bacterial lipoproteins, mycoplasma lipoprotein, mycobacterial lipoarabinomannan, a phenol-soluble modulin from S. epidermidis, zymosan of yeast cell walls, and lipoglycosylphosphotidylinositol T. cruzi â⬠¢ Also shown to recognize two kinds of atypical LPS: L. interrogans and Porphyromonas gingivitis Toll-like receptor 3 (TLR3) Receptor for dsRNA â⬠¢ Can mediate responses to poly(IC) â⬠¢ Expressed on DCs, macrophages, and surface epithelial cells, including instestinal epithelium â⬠¢ Also expressed in CD8+ DCs Toll-like receptor 7 (TLR7) â⬠¢ Involved in viral recognition and both detect nucleic acids together with TLR9 â⬠¢ Recognizes viral ssRNA (derived from RNA viruses); TLR9 (unmethylated DNA derived from DNA viruses) â⬠¢ Expressed primarily on plasmacytoid dendritic cells â⬠¢ Activated by small antiviral compunds, e. g. imiquinoid â⬠¢ TLR7-mediated recognition takes place inside the late lysosomes Toll-like receptor 9 (TLR9) â⬠¢ Involved in the antiviral host defense; especially on recognition of DNA viruses (HSV) â⬠¢ Expressed in type-I INF-producing plasmacytoid DCs Phagocytic Receptors â⬠¢ Scavenger receptors ââ¬â cell-surface glycoproteins that are defined by their ability to bind to modified LDL â⬠¢ Macrophage Mannose Receptor (MR) ââ¬â type I transmembrane protein expressed primarily in macrophages; involved in phagocytosis of bacterial (MTB, P. eruginosa, K. pneumonia), fungal (S. cerevisae, C. albicans), and protozoan pathogens (P. carinii) Cells of the Innate Immune System â⬠¢ Macrophages ââ¬â most central and essential functions and have multiple roles in host defense (e. i. ââ¬Å"housekeeping functionsâ⬠); in red pulp of the spleen, it phagocytose and remove from circulation senescent RBCs â⬠¢ Neutrophils â⬠¢ Mast Cells ââ¬â best known effectors of aller gic response; protective role is by rapid production of TNF-? nd leukotriene B4 (neutrophil recruitement) Cells of the Innate Immune System â⬠¢ Eosinophils ââ¬â found primarily in the respiratory, intestinal, and genitourinary tracts; contains cationic effector proteins toxic to parasitic worms; poor phagocytes â⬠¢ Dendritic Cells ââ¬â immature DCs reside in peripheral tissues and are highly active in macropinocytosis and receptor-mediated endocytosis; expresses PRRs and TLRs; have roles in the initiation of adaptive immune response Cells of the Innate Immune System Suface Epithelium ââ¬â lines the mucosal surfaces of the intestinal, respiratory, and genitourinary tracts provide an important physical barrier The Effector Mechanisms of the Innate Immune System The Major Categories of Antimicrobial Effector Enzymes that hydrolyze components of microbial cell walls Antimicrobial proteins and petides that disrupt the integrity of microbial cell walls â⬠¢ Lysozyme â⬠¢ Chitinases â⬠¢ Phospholipase A2 â⬠¢ â⬠¢ â⬠¢ â⬠¢ â⬠¢ BPI Defensins Cathelicidins Complement Eosinophil cationic protein Microbicidal serine proteases Proteins that sequester iron and zinc Enzymes that generate toxic oxygen and nitrogen derivatives â⬠¢ Seprocidins â⬠¢ Lactoferrin â⬠¢ NRAMP â⬠¢ calprotein â⬠¢ Phagocytic oxidase â⬠¢ Nitric oxide synthase â⬠¢ myeloperoxidase The Effector Mechanisms of the Innate Immune System â⬠¢ Lysozyme ââ¬â a. k. a. muramidase; degrades the peptidoglycan of some gram(+) bacteria; highly concentrated in secretions such as tears and saliva â⬠¢ Chitinases ââ¬â enzymes that degrade chitin; secreted by activated macrophages and presumably play a role in antifungal defense The Effector Mechanisms of the Innate Immune System â⬠¢ Defensins ââ¬â cationic peptides with a broad spectrum of antimicrobial activities against gram(+) and gram(-) bacteria, fungi, parasites, and some envelope viruses; kill microorganisms by forming pores in the membranes; divided into ? ââ¬â and ? defensins â⬠¢ ? -defensins ââ¬â presynthesized and stored in granules of neutrophils and Paneth cells of the small intestine â⬠¢ ? -defensins ââ¬â produced by epithelial cells and not stored in cytoplasmic granules The Effector Mechanisms of the Innate Immune System â⬠¢ Cathelicidins ââ¬â active against gram(+) and gram(-) bacteria and fungi; produced in neutrophils and stored as inactive proproteins in the secondary granules â⬠¢ Serprocedins ââ¬â comprise a family of cationic serine proteases with antimicrobial activity (neutrophil elastase, proteinase 3, cathepsin G, and azurocidin); exert its antimicrobial activity by either perturbation of microbial membranes or by proteolysis The Effector Mechanisms of the Innate Immune System â⬠¢ Lactoferrin, NRAMP, and Calprotectin ââ¬â antimicrobial activities are due to the ability to sequester iron and zinc â⬠¢ Lactoferrin ââ¬â found in the secondary granules of neutrophils, in epithelial secretions (e. i. breast milk), in the intestinal epithelium of infants, and in airway fluids; bacteriostatic (iron sequestration) and bacteriocidal (perturbation of microbial membranes) The Effector Mechanisms of the Innate Immune System NRAMP (natural resistance-associated macrophage protein) ââ¬â integral membrane protein that functions as an ion pump in the phagocytic vacuoles of macrophage and neutrophils â⬠¢ Calprotectin ââ¬â member of the family of calciumbinding proteins; microbial activity is by chelation and sequestration of zinc ion ACUTE PHASE REACTANTS â⬠¢ Soluble factors which are normal constituents that increase or decrease rapidly as produ â⬠¢ Not a function of a single defined ph ysiologic system; rather, it is a product of multiple and diverse defense mechanisms How to cite Medical Immunology, Essay examples
Thursday, December 5, 2019
The Poetic Facts Of Life Essay Example For Students
The Poetic Facts Of Life Essay Stephen Hawking is the man who has tried to explain The Universe in a Nutshell. He might deserve a prize just for a title that sums up what popular science books are all about. The metaphor for Hawkingââ¬â¢s bid to enclose the great mystery of the universe in 200 pages contains a kernel of truth. You really could use a nutshell as a text for a sermon about creation. The hydrogen in its chemical makeup was hammered into existence 15 billion years ago, in the first seconds of time itself. The carbon, nitrogen, phosphorus and so on that make up the rest of it were forged in the thermonuclear furnace of a star. In dying, this star showered an explosion of elements across the vastness of space, some of which were swept up in the formation of a new star, surrounded by a suite of nine planets, one of which was just small enough, warm enough and solid enough to act as a stage for yet more improbable events. Somewhere on this planet, in a warm little pond, or near a submarine volcano, or on a sunlit beach, chemistry became biochemistry. Life emerged from a haphazard series of chemical events. Life requires resources and energy. The first were supplied by the dust from the long-dead star, the second came from the newborn sun. Green things evolved, consuming the original atmosphere of carbon dioxide, building tissue from carbon and other elements, and discarding the oxygen as waste. Fleshy, oxygen-breathing things evolved, to feed on plants and consume oxygen and exhale carbon dioxide, to keep the cycle going. So in the tissue of the nutshell there lies the whole epic of creation, from Big Bang to stardust, from nut to nuthatch. Novelists and poets look for their stories from within the human experience. Science books at their best provide a kind of crib for the true script of creation. Science writers look outwards, and decipher the narrative of time in the stars, the rocks, and the cellular tissue of life. They also emerge with a wonderfully literal kind of poetry. Our destiny may not be written in the stars, but our past certainly is. Blake sang of seeing the world in a grain of sand. Hannah Holmes ââ¬â with Stephen Hawking, one of the six authors in pursuit of a ? 0,000 Aventis science book prize tonight ââ¬â perhaps unconsciously picked up Blakeââ¬â¢s idea and produced another potential winner in The Secret Life of Dust. This is an epic about the bits of dead skin, eroded mountain, pounded bone, decayed wood and burnt oil that shift across the planet every second of the day, shaping continents and shaping lives. Blake also sang of holding infinity in the palm of your hand and eternity in an hour. Hawking picked up Blakeââ¬â¢s challenge. So did Martin Gorst, author of Aeons. Archbishop Ussher in the 17th century calculated, using the chronologies of the Bible, that the world had been created in 4004 BC. But later researchers ââ¬â many of them also churchmen ââ¬â looked not at books but at the writing in the dust and the rocks and the heavens and came to a different conclusion. Gradually, they pieced together an ever-expanding history of time in an ever-expanding universe, and helped put human presumption in its place: on a speck of rock circling an unimportant star in a galaxy of 100bn stars in a universe of at least 100bn galaxies. But Blake also saw heaven in a wildflower. So far, planet Earth is the only place in the universe known to have produced flowers, or intelligent animals. Robert Sapolsky, in A Primateââ¬â¢s Memoir, and David Horrobin, in The Madness of Adam and Eve, address the emergence of social behaviour in primates and the part schizophrenia might have played in the making of human intelligence. Both books look not at the great sweep of research into the universe but the exhilarating debate within science itself, about why humans are as they are, where they might have come from and where they might be going. .u88ddac289ed285ca4edf0e39565fdefe , .u88ddac289ed285ca4edf0e39565fdefe .postImageUrl , .u88ddac289ed285ca4edf0e39565fdefe .centered-text-area { min-height: 80px; position: relative; } .u88ddac289ed285ca4edf0e39565fdefe , .u88ddac289ed285ca4edf0e39565fdefe:hover , .u88ddac289ed285ca4edf0e39565fdefe:visited , .u88ddac289ed285ca4edf0e39565fdefe:active { border:0!important; } .u88ddac289ed285ca4edf0e39565fdefe .clearfix:after { content: ""; display: table; clear: both; } .u88ddac289ed285ca4edf0e39565fdefe { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .u88ddac289ed285ca4edf0e39565fdefe:active , .u88ddac289ed285ca4edf0e39565fdefe:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .u88ddac289ed285ca4edf0e39565fdefe .centered-text-area { width: 100%; position: relative ; } .u88ddac289ed285ca4edf0e39565fdefe .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .u88ddac289ed285ca4edf0e39565fdefe .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .u88ddac289ed285ca4edf0e39565fdefe .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .u88ddac289ed285ca4edf0e39565fdefe:hover .ctaButton { background-color: #34495E!important; } .u88ddac289ed285ca4edf0e39565fdefe .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .u88ddac289ed285ca4edf0e39565fdefe .u88ddac289ed285ca4edf0e39565fdefe-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .u88ddac289ed285ca4edf0e39565fdefe:after { content: ""; display: block; clear: both; } READ: Poetry EssayIt could be the most important lesson to be gained from popular science books: that science is as much about questions as about answers, about argument as well as about discovery. Indeed, the outsider in the Aventis prize, Rivals, by Michael White, is about the often bitter disputes that have raged within science. Pollsters from time to time show that people donââ¬â¢t ââ¬Å"trustâ⬠scientists. But this could be a sign of a healthy attitude, rather than a cynical one: scientists are human, and therefore capable of folly. Science, too, moves on: Professor Hawking became the publisherââ¬â¢s dream author more than a decade ago when his A Brief History of Time notched up 6 million copies in hardback alone. But he would not now write the same book. That is because science is an unfolding story of an adventure that will end only when humans do. Tune in for the next episode. The annual Aventis science book prize will be announced tonight.
Thursday, November 28, 2019
Egypt And Mexican Culture Essays - Architectural Styles, Egyptology
Egypt And Mexican Culture For many centuries people have been fascinated by ancient cultures and treasures. During the last two centuries the science of archeology and modern inventions allowed people to get inside of the Egyptian and Mayan pyramids and discover the treasures of Egyptian pharaohs and Mayan rulers. Most of what we know about Egypt we owe to the pyramids. Thanks to Egyptian belief in the afterlife we can now find out about the civilization that existed nearly five thousand years ago. Egyptian culture is not the only culture that left us its heritage in pyramids. In America we find pyramids build by civilizations of Olmec and Maya about 7th century CE. These pyramids had different purposes and usage then the ones in Egypt but they stand as memorials to ancient civilizations as well. Egyptian people believed in life after death. One of the way pharaohs prepared themselves for the afterlife journey was by building a pyramid and putting there all their belongings and riches. Egyptian people believed that pharaoh is the closest person to the God and treated him accordingly. That is the reason for Egyptian tombs being full with the golden jewelry, precious stones and art objects. Most of the time art objects were not considered a treasury but they played their particular role in religious rituals. Jars were holding food and drinks for pharaoh's journey, so he would not get hungry and would have food and drinks to offer to the Gods. The figurative sculptures were suppose to accompany Ka ( spiritual entity) in its lonely stay or serve as a twin for the mummy. If something happens to the mummy the ka could use the sculpture of the pharaoh for the revelation. As well as for Egyptians religion was an everyday concern for many of the Maya, whether the dynastic ruler, the zealous priest, or the humble believer. Maya has an extensive religion structure which we can not know in details. Chac and Itzamna are the most famous gods of Mayan culture. Hunahpu and Xbalanque are among the most interesting mythical characters. One of the most crucial gods was Tlaloc, who was worshiped in various guises by the culture of Teotihuacan, the Toltec of Tula, and later Aztecs. The Maya received the cult of Tlaloc during the 4th century more or less. The Cauac Monster, also known as the Witz monster, is a dominant supernatural concept in Maya religion, as are caves, cenotes, and other holy places (Maya Civilization pars. 6). The Maya built shrines, temples, and pyramids in honor of their gods, as well as to their kings, who ruled by all-encompassing concept of Divine power. Most of Mayan pyramids are temples to the gods, not the burial tombs as in Egypt. Even though Maya sometimes buried there their rulers they always put the temple on the top of the pyramid. Egyptians had temples near the pyramid or right next to it for the ceremonial services, but it never was placed on top of the structure. Also buildings in both cultures have a lot in common in their visual characteristics they are different structures. Egyptian pyramids originally had smooth equal sides meeting on the top in the perfect apex. Mayan pyramids look like one huge stairway towards the sky. It reminds of earliest Egyptian structures-mastabas, where one layer of stones was put onto another creating the effect of pyramid. Also The Tikal Temple on Great Plaza was originally plastered white. Then the roof comb was painted with reds, blues, and other colors to accent the different areas of sculptural decoration. These roof combs were like giant billboards, with immense portrayals of the enthroned king, larger then life size (Cities pars.3). Egyptians never colored their religious structures. As well as in Egyptian pyramids, the stone used to construct Mayan pyramids is local limestone, obtained from nearby quarries. The ancient Maya had no stone tools but limestone is soft enough that the Maya could utilize chert tools to work the stone in to neat rectangular building blocks. Egyptian pyramids served as huge tombs and they were constructed in such a way so they would stand for thousand years. Egyptians did not know when the spirit would return into the dead body. Pyramids were constructed of rough stone blocks laid in horizontal rows, in a polygonal shape, with triangular sides rising to meet in the apex. Some were originally as high as 750 feet. The pyramids were built by taking blocks of granite to the workshops, measuring the blocks down the size, shaping the block and placing
Sunday, November 24, 2019
Special Effects essays
Special Effects essays When you see a commercial, and animals are talking to each other and having human expressions you think, how did they do that? The answer is special effects. When you look at commercials, movies, cartoons, all of them have some sort of special effect. With the technology becoming better we begin to see more and different types of special effects. As with the movie Toy Story, being created all by computer, it was the first of its kind. As the times and movies progressed we have seen the increased usage of special effects and the steady improvement of the quality of the special effects. If we did not use Special Effects the revolution of movies would be really slow and boring and movies would be really basic. With Special Effects in movies we can create endless possibilities and bring dreams, illusions, and fantasies to life. Using special effects, we have brought dinosaurs, aliens, and other monsters to life. We have destroyed cities, people, and planets with special effects also. With computers we are able to create sceneries we would never think possible. With the help of computers we can create people, buildings, animals, monsters, aliens, and many other creations. Our creations in the computers can come out to life with a touch of a button. Special Effects are both an art and a science. The "science" part involves the complete understanding of how the audio-visual sensory parts of our body and brain perceive the world around us, while the "art" part involves the strategic use of this information to fool the sensory system. Without knowing what special effects is, it would be hard to understand what is necessary and needed to produce a good movie with special effects. Now there are two basic kinds of effects, computer generated and humanized effects. Computer generated effects consist of the Blue Screen/Matte, Computer Animation, and Composting. A blue screen/matte is when the foreground and backgro...
Thursday, November 21, 2019
Health Risks and Benefits of Circumcision Research Paper
Health Risks and Benefits of Circumcision - Research Paper Example The main risk associated with circumcision is primarily credited to the surgical procedure itself. In a study conducted in the University of Washington, the authors were able to establish that out of 130,000 boys who had circumcisions at the Washington state hospital, 287 of them developed complications in relation to the procedure. The most common complications seen were intraoperative bleeding (230 cases) and damage to the penis (52 cases). The authors comment however that these are preventable risks which would still be outweighed by the benefits of circumcision. Most of the complications associated with circumcision are minor and are very much localized. Meatal stenosis is seen in circumcised males and is said to follow intraoperative vascular injury to the frenular vessels. Due to meatal stenosis, there may be a deflection of the urine system or in some cases; dysuria and occult hematuria may also be seen in the circumcised male. Reports of skin bridges forming when separated fo reskin come in contact with each other are sometimes also manifest in circumcised males, and this can cause pain and penile curvature during erection. Before the advent of improved anesthesia options, the neonatal pain experience has been emphasized as one of the main objections against circumcision. The pain experience is known to cause physiological responses, such as increased heart rate, respiratory rate, and serum cortisol level, lower serum oxygen saturation and lower vagal tone.
Wednesday, November 20, 2019
Geico ad campaigns and how they made the company successful Research Paper
Geico ad campaigns and how they made the company successful - Research Paper Example dvertisement campaigns strategy of GEICO integrates within it, and incorporates a vivid amount of mail circulars, radio advertisements, television parody and other forms of advertisements. The company has primarily utilized the punch line, which is "fifteen minutes could save you fifteen percent or more on car insurance." According to the owner of GEICO, Warren Buffett, approximately more than 40% of Americans are capable of making big savings on their money by utilizing the services and features of GEICO. He also mentioned that, if possible, then he could even have invested $2 billion merely on the advertisements of the company. There have been numerous advertisements of GEICO which have become the memorable one shot ads. They include many the following: A man owns a dog who wears a fire propinquity suit and a man's dog wears a fire proximity suit as he distributes the insurance companyââ¬â¢s competing bill for the reason that it is "too hot to handle". The duck is on the adverti sement and is found saying (while clearing throat), "Am I on? GEICO could save you hundreds of money on car insurance. Result..." The bill is then removed by the duck and, in its place, a smaller bill is shown, while saying, "...Smaller bill." Another impressive advertisement shows that a long distance phone call is placed by a man through the operator. He uses the code name Bob Wehaddababyitsaboy in order to evade the call charges which could be billed to the recipient of the call. This commercial was run on for several weeks over the televisions and was named joke and had a pitch for GEICO. The ad was accompanied by the shot of a man who was shown further exploiting his name trick on the telephone. He was seen saying "Last name is Wehadababyitsaboyandweighs8pounds3ouncesandisdoingfine". This... Geico Ad Campaigns In the current era of increasing modernization, technical advancements and upgradations, the companies have widely taken the opportunities offered by the diverse media to present their distinctly produced goods and services.There have been numerous advertisements of GEICO which have become the memorable one shot ads.They include many the following: A man owns a dog who wears a fire propinquity suit and a man's dog wears a fire proximity suit as he distributes the insurance companyââ¬â¢s competing bill for the reason that it is "too hot to handle".ïÆ'Ë The duck is on the advertisement and is found saying (while clearing throat), "Am I on? GEICO could save you hundreds of money on car insurance. Result..." The bill is then removed by the duck and, in its place, a smaller bill is shown, while saying, "...Smaller bill." ïÆ'Ë Another impressive advertisement shows that a long distance phone call is placed by a man through the operator. He uses the code name Bob Wehaddababyitsaboy in order to evade the call charges which could be billed to the recipient of the call. This commercial was run on for several weeks over the televisions and was named joke and had a pitch for GEICO. The ad was accompanied by the shot of a man who was shown further exploiting his name trick on the telephone. He was seen saying "Last name is Wehadababyitsaboyandweighs8pounds3ouncesandisdoingfine". This commercial had captured the attention of many viewers and had increased the popularity of the company.
Monday, November 18, 2019
Critically examine how effective the Single European Act has been in Essay
Critically examine how effective the Single European Act has been in creating a European Internal Market - Essay Example Through a historical overview of the treaties upon which the EU is founded, followed by a discursive analysis of the enlargement process, the creation of joint borders through the Schengen Agreement, and the formulation of a monetary regime whose outcome was he implementation of a single EU monetary unit, the research shall demonstrate that while the SEA contributed to both the deepening and the fortification of the integrative process, it is hardly single-handedly, or even primarily, responsible for the evolution of the EU of 2005. The European Union is a unique example of political economic integration. Even though Paul and De Burca date the creation of the EU to the birth of the Maastricht Treaty in 1993, others have contended this to be erroneous, insisting that the evolutionary process spanned five decades. This argument is forwarded by Molle (2001) and expressed in his contention that evolved from a limited common market with only six member states to a regional political and economic bloc, comprising twenty-five nations, in the span of five decades, the European Union provides political economists and legal scholars with a unique insight into the legal strategies and frameworks requisite for the realization of such an ambitious project. The European Union project, as noted by Molle (2001), was predicated on the assumption that regional political and economic unification could restore European global economic and political power and with this assumption functioning as a prime motivator, legislature and tr eaties among towards the realization of the stated goal, entered the formulation stage I 1948 and the implementation stage in 1952 (Molle, 2001). 1952 witnessed the passage and implementation of the EUââ¬â¢s founding treaty, the Treaty of Paris. At this stage, the European integration process was confined to the creation of the
Friday, November 15, 2019
Human Rights as a Global Issue
Human Rights as a Global Issue This essay will aim to explain and describe human rights, how it was recognised and how it is rapidly becoming a global issue in various countries. The essay will also go further to discuss Benthamââ¬â¢s theory relating to human rights and analyse the values of human rights with and without laws to protect them. Firstly, according to MM Wallace and Martin-Ortega ââ¬Å"human rights are regarded as those fundamental and inalienable rights essential for life as a human being.â⬠[1] Human rights are known to be the fundamental rights that belong to all and as such everyone is entitled to have these rights. There have been different ideas on human rights over past centuries; however it received international support as a result of the holocaust and the Second World War. As a result of this, the United Nation adopted the Universal Declaration of Human Rights in 1948 which sets out to protect human rights in various countries, to create awareness to individuals, to serve as a benchmark, to educate individuals on their rights, to serve as a political tool. There are different bodies under the United Nations that manage the affairs of human rights and these are the Human Rights committee, the Human rights commission which was replaced by the Human rights council. These bodies enforce and aim to maintain human rights laws in different countries to a certain extent. There are three different human right laws which are enforced and monitored in different ways; these are the international law, the regional law and the domestic law. According to the oxford dictionary international law ââ¬Å"is a body of rules established by custom or treaty recognised by nations as binding in their relations with one another.â⬠[2]The international law protects human rights globally and it consists of treaties and conventions such as International Convention on Civil and Political Rights, the United Nations Convention on Rights of a Child and the United Nations Convention against Torture. Apart from international law, the regional law is also used to protect rights and it consists of home-group treaties such as the European Convention on Human Rights, the African Charter on Human and Peopleââ¬â¢s Rights and the American Convention on Human rights. Other than this, there is also domestic law that also serve the same purpose as the international and regional laws. Many countries have their own domestic human rights legislation which sets out to protect the rights of the citizens. For example, the United Kingdom has the Human Rights Act 1998 which came into force on 2nd October 2000. Looking at the points made above, it is clear to see that these laws support and implement human rights. Human rights are essential but without the law they have no real values. According to Benthamââ¬â¢s theory; he states that ââ¬Å"natural rights are simple nonsense: natural and imprescriptible right, rhetorical nonsense- nonsense upon stilts.â⬠[3] Bentham was stating that natural rights are nonsense because he believes that rights are things that cannot be seen and if these so called rights cannot be seen then the existence of them is actually unknown. He also goes further to explain that human rights are given to individuals by the sovereign because it is the sovereign that makes the laws and therefore the laws should back up human rights, so in essence human rights have to exist with the law or without it, it is valueless. In addition to this, human rights need to have laws to guide them so as to avoid infringement upon individualââ¬â¢s rights by the government which may lead to conflict and dispute which could eventually escalate to war. Furthermore international law can protect rights through the use of international trade. In international trade there are sanctions that are given to some countries that violate the human rights laws and these are known as embargos, tariffs and quotas. An embargo is the complete prohibition against importing foreign goods into the country while the tariffs are taxes that are placed on imported goods in a country. The quotas are limits on the amount of a particular good that should be imported into a country. The embargo is the most commonly used sanction for states that go against the law and it has proven to be effective to a certain extent. The embargos are imposed by the UN or the EU; examples of countries that have been embargoed from the United States are North Korea, Syria, Cuba, Iran, Somalia, Sudan and Libya. Although one can see that law is really needed to protect human rights but international law can be criticised. International law is ineffective and inefficient to a certain extent because there are still reports on the infringement on human rights in different countries. An example is North Korea where human rights are being abused; this shows that even with the existence of international law and the United Nations some countries can ignore the laws since it is non-legal bound and a good example of international law is the UDHR (Universal Declaration of Human Rights). Apart from this, international law is difficult to enforce as a result of the non-legal bound factor and therefore this will prove a difficult task for the United Nations. Another demerit of international law is that some sanctions that are imposed on some countries do not affect them. The embargo which is a form of sanction does not affect some powerful countries because without trade these countries can still survive and grow with their resources. Human rights can also be valued without the implementation of the law; Bentham explains that human rights are just ideas but nevertheless they are there and they are recognised by the United Nations. The knowledge of these rights has real values in the sense that the citizens of a country can pressure the government into giving them their rights since they are aware of it. This act which can be viewed as rebellion against the government can either be carried out by interest groups or pressure groups. The student room article explained that ââ¬Å"pressure groups are organised groups of people who come together, usually outside of the government, with a common cause with the intention of influencing government policy and public opinion.â⬠[4] The statement above shows that pressure group are groups of individuals that come together to pursue a common interest in the society. Pressure group is essential in every democratic society because it represents and promotes the principle of freedom of speech and freedom of association inherent in democratic settings. Fagan states ââ¬Å"the expression of opinions and views is widely considered a fundamental attribute of individual freedom.â⬠[5] Pressure groups adopt different methods to promote their interests and these are lobbying, campaign, strike, protest and boycott. One of the major benefits of pressure groups is that it promotes democratic principles of freedom of speech therefore allowing individuals to express their opinions. Apart from this, another benefit is that it promotes democratic principles of criticism which indirectly checks the power of the government. However pressure groups have been known to be very destructive, especially during the period of direct action such as a protest and this can eventually lead to retrogression in the society. Not only can this happen but it can also lead to civil war whereby a considerable number of citizens will be killed. In addition to this, human rights that have no law to support them have its disadvantages. One of which is the fact that the government can still infringe on the citizenââ¬â¢s human rights even if they attempt to rebel against the government. An example of a country where such act can be seen is Syria; in Syria a civil war has occurred because of the uprising against the regime of the president Bashar al- Assad in March 2011. The Syrian civil war is also a part of the Arab spring uprisings in the Middle East. The Arab spring can be said to be the media term for a revolutionary wave of violent and non-violent demonstrations such as protest, riots and civil war in the Arab world. T he Arab spring which is still a global issue in the modern world has also been able to prove that without law to protect human rights it has no real values. In conclusion, human rights have no real values without the law to protect it. Referring back to the points made, it can be seen that having the knowledge of these rights are not substantial because human rights abuse will still occur but if the law is implemented, human rights can still be protected to a certain limit showing that with law human rights have real values. 1 [1] Wallace MM R. Martin- Ortega O, INTERNATIONAL LAW, 7TH EDITION, 2013, Sweet and Maxwell [pg 240] [2] INTERNATIONAL LAW, www.oxforddictionaries.com [accessed 19th February, 2014] [3] George H. Smith, Jeremy Benthamââ¬â¢s attack on Natural rights, June 26 2012, www.libertarianism.org [accessed 18th February, 2014] [4] THE STUDENT ROOM, PRESSURE GROUP,www.thestudentroom.co.uk [accessed 19th February, 2014] [5] Fagan A, THE ATLAS OF HUMAN RIGHTS, Myriad editions, 2010, Earthscan Ltd, [pg 40]
Wednesday, November 13, 2019
Chopins Lilacs and the Story of the Annunciation :: Chopin Lilacs Essays
Chopin's Lilacs and the Story of the Annunciationà à à à à à à à à à When the theologian Elisabeth Schussler Fiorenza writes that the myth of the Virgin Mary "sanctions a deep psychological and institutional split" (59) among women in the Catholic tradition, she captures what Kate Chopin also captured in her story "Lilacs." There, sisterhood between secular and religious women appears fragmented and nearly impossible. To scrutinize the division, Kate Chopin fashions her story around the portion of the Virgin Mary myth told in St. Luke's gospel of the Annunciation of the birth of Jesus spoken to Mary by the archangel Gabriel. Working with that text, "Lilacs" mocks a tradition prizing virginity and separating the cloistered from the secular. Irony prevails, but so too does the sorrow born of religious restraint and condemnation. From the tension in the Annunciation between the virginal and the non-virginal comes ages of women divided from one another on the basis of chastity and divided internally into spiritual and physical selves. à Chopin's "Lilacs" plays out this division on the grounds of a Sacred Heart convent and in the apartments of a Parisian mondaine to question whether a life almost wholly spiritual or a life almost wholly physical can be anything but the subject of ridicule. The narrator tempts us to enjoy the ridicule only to have us feel more painfully at the story's end the dolorous effects of con strained desire, effects which diminish both nun and secular woman. à As a story that draws so heavily on the details and symbols of the Annunciation story, "Lilacs," we could assume, would want to remind us of Mary's (and, by extension, woman's) salvific role as the vessel chosen by God to ensure humankind's redemption. But "Lilacs" fails to announce the good news for women as it sees too clearly that what was salvific for humankind ended up dividing women within themselves and within the Catholic tradition because of that tradition's insistence on Mary's virginity before and after childbirth. This insistence separated the ideal virginal mother from real women and mothers whose joyously experienced sexuality closed the doors to work within the clerical ministry even until today. The Annunciation story for Kate Chopin is a story told at the expense of women's sexuality and spirituality, full and complementary as they might have been. The notion of a failed annunciation, then, opens "Lilacs": "Mme. Adrienne Farival never announced her coming.
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